The group of therapists provides a support network to the professionals involved in ATraPA. CONCLUSIONS ATraPA has been successfully implemented in a Child and Adolescent Psychiatry Service within the Spanish national health system. Future studies should address the efficacy of ATraPA using a controlled design. © 2020 John Wiley &amp; Sons Australia, Ltd.BACKGROUND The Patient-Reported Outcomes Measurement Information System (PROMIS) includes multiple domains that measure pain and physical functioning which are valid and reliable for use in children with sickle cell disease. The responsiveness of these measures to detect changes in health status over time among children with sickle cell disease is unknown. PROCEDURE We conducted a prospective cohort study of children presenting to emergency department (ED) with vaso-occlusive crises. Children completed PROMIS surveys in the ED and at two follow-up time points (7-10 days and 1-3 months) after their acute care visit. Linear mixed models were used to determine if there were significant changes in PROMIS T scores over time. We used a patient's global assessment of change in pain question to anchor the changes in PROMIS scores (mean and 95% confidence interval). A change was considered statistically significant if the 95% CI did not include 0. https://www.selleckchem.com/products/OSI-906.html RESULTS We found that patients improved significantly in all domains 1 to 3 months after discharge from an acute care visit for pain. In addition, the pain and physical stress experience domains were responsive to change 7 to 10 days after discharge. Using the anchor of change in pain, for children who had considerable improvement in pain, there were significant changes in PROMIS T scores ranging from 6 to 15. CONCLUSIONS Relevant PROMIS domains detect changes in children experiencing acute vaso-occlusive crises. These domains can be used in research and clinic settings to measure clinically relevant change in children with sickle cell disease. © 2020 Wiley Periodicals, Inc.We hypothesized that late gestation malnutrition differentially affects expandability of adipose tissues to predispose for early postnatal visceral adiposity. Twin-lambs born to dams fed HIGH (150%/110% of required energy/protein, respectively), NORM (100% of requirements) or LOW (50% of NORM) diets during the last trimester were used. Postnatally, lambs were raised on moderate (CONV) or high-carbohydrate-high-fat (HCHF) diets. Adipose tissues were sampled at autopsy at 6&nbsp;months of age (~puberty) to characterize cellularity, adipocyte cross-sectional area and gene expression patterns. HIGH and LOW compared to NORM lambs had reduced intrinsic (under CONV diet) cellularity in subcutaneous and mesenteric (particularly LOW), and reduced obesity-induced (under HCHF diet) hyperplasia in subcutaneous, mesenteric and perirenal (particularly HIGH) adipose tissues. This corresponded with more pronounced HCHF diet-induced hypertrophy in mesenteric (particularly LOW), perirenal (particularly HIGH) and subcutaneous (particularly HIGH) adipose tissues, and tissue-specific reductions in mRNA expressions for lipid metabolism, angiogenesis and adipose development. Gene expression for inflammation and lipid metabolism markers were increased and decreased, respectively, in HCHF lambs (HCHF lambs became obese) in all tissues. Both prenatal over- and undernutrition predisposed for abdominal adiposity and extreme perirenal hypertrophy due to reduced intrinsic (observed under CONV diet) cellularity and impaired ability of subcutaneous, mesenteric and perirenal adipose tissues to expand by hyperplasia rather than hypertrophy on an obesogenic (HCHF) diet. © 2020 The Authors. Physiological Reports published by Wiley Periodicals, Inc. on behalf of The Physiological Society and the American Physiological Society.AIM This is a descriptive longitudinal study conducted to identify the effects of the perception of child value by parents on parenting stress, controlling parenting attitudes, and children's self-esteem. METHODS The present study targeted parents aged 19?years or older and their children who participated in the fourth through to the eighth Panel Study on Korean Children. The study examined the longitudinal relationship of the effect of parental factors on self-esteem in children, and applied an actor-partner interdependent model to analyze the effect of interactions with parents. RESULTS The paternal instrumental value had a partner effect on the rate of change in maternal parenting stress, while the maternal instrumental value of children had an actor effect on the rate of change in maternal parenting stress. The baseline value of parenting stress had an actor effect on the baseline value of controlling parenting attitudes, while the rate of change in maternal parenting stress had a partner effect on paternal controlling parenting attitudes and an actor effect on the rate of change in maternal controlling parenting attitudes. The baseline value and rate of change in controlling parenting attitudes were found to influence self-esteem in children. CONCLUSION Reducing parenting stress by increasing the parents' positive perception of the value of children can be helpful in maintaining a consistent parenting attitude by parents, which can have a positive effect on self-esteem in children. It is important to provide intervention and management of variables related to self-esteem in children using a long-term and multidimensional approach. © 2020 Japan Academy of Nursing Science.Breastfeeding has numerous health, environmental, and economic benefits, and the promotion and support of breastfeeding has been at the centre of efforts from many global organizations such as WHO and UNICEF to promote maternal and child health. Interventions developed from such policies tend to be inaccessible to those who are economically marginalized, however, and thus may further inequities. Understanding the lived experiences of women occupying this segment of society, such as sex workers, illuminates the social and structural determinants of breastfeeding and how they constitute structural vulnerability that renders breastfeeding difficult. This qualitative study explores breastfeeding practices and decisions among sex workers in Mumbai and the factors shaping their experiences. We look at proximal factors-those that women directly indicate as influencing their breastfeeding decision-making or behaviour, and distal factors-macrolevel forces identified by the women, as indication of their structural vulnerability, particularly in relationship to the decision to initiate and sustain breastfeeding.